Atherosclerosis and Other Side Effects of Tasigna®
Tasigna® has been linked to atherosclerosis; a buildup of plaque or fatty deposits in the arteries. This condition can cause serious side effects that may lead to death.
Atherosclerosis/ Hardening or Narrowing of Arteries
Atherosclerosis (also known as hardening or narrowing of arteries) is a condition where fatty deposits called plaque buildup in arteries. The buildup of plaque results in the artery wall getting thicker, narrowing the opening and reducing blood flow. In advanced atherosclerosis, arteries can become completely blocked; a blocked artery in the heart is a heart attack, a blocked artery in the brain is a stroke, and blocked arteries to arms and legs can lead to gangrene (tissue death) and require amputation.
A stroke is caused when blood flow to the brain is cut off and brain cells deprived of oxygen die. The abilities controlled by brain cells that die, such as speech and muscle control, are lost.
When the heart is deprived of oxygen-rich blood, it can cause angina; pain or discomfort that feels like pressure or squeezing. The pain can happen in the chest, back, neck, jaw, shoulders, or arms.
When the flow of blood carrying oxygen to the heart is severely reduced or completely cut off, it is called ischemia. If the ischemia causes damage or death to part of the heart muscle, it is called a myocardial infarction or heart attack.
Limb amputation associated with Tasigna® results from blocked arteries to the arms and/or legs. When the arteries are blocked, it leads to gangrene and necessitates amputation.
Serious Blood Clots
An embolic occlusion, also known as a thrombosis or blood clot, is a blockage cutting off blood flow in an artery, often from the buildup of plaque in the arteries.
Serious Blood Clots
Tasigna® is linked to embolic occlusion, also known as a thrombosis or blood clot; a blockage cutting off blood flow in an artery, often from the buildup of plaque in the arteries.
Carotid Artery Disease
Carotid arteries are located on each side of the neck. They divide into the internal and external carotid arteries; the internal carotid artery carries blood to the brain while the external carotid artery carries blood to the neck, face, and scalp. Carotid artery disease occurs when plaque builds up in the carotid artery which can lead to stroke.
Coronary Artery Disease
Coronary artery disease (also known as C.A.D., Coronary arteriosclerosis, Coronary atherosclerosis) is one of the leading causes of death in the United States for both men and women. This disease occurs when the arteries supplying blood to the heart become narrow or harden due to the buildup of plaque or other materials. As coronary artery disease progresses, the narrowing and/or hardening of the arteries can lead to pain, a heart attack, or death.
Peripheral Artery Disease
Arteries that carry blood to your head, organs, and limbs are called peripheral arteries. Peripheral artery disease (also known as P.A.D.) occurs when these arteries harden or narrow due to the buildup of plaque, calcium, or other materials. This disease usually affects arteries in the legs, but it may also affect arteries carrying blood from your heart to your arms, head, and internal organs.